Notable alumni/ae of the SU fraternity and sorority system include radio and television personalities, athletes, and prominent businessmen and women.

Among this illustrious group are:

Dick Clark, CEO of Dick Clark Productions, a member of the Delta Kappa Epsilon Fraternity.

Betsey Johnson, Fashion Designer, a member of the Alpha Xi Delta Sorority.

Ted Koppel, news correspondent and commentator, a member of the Pi Kappa Alpha Fraternity.

Darryl Bell, actor, and member of Alpha Phi Alpha Fraternity, Inc.

Angela Jones-Tate, financial mogul and member of the Alpha Kappa Alpha Sorority, Inc.

John W. Georgas, senior vice president of the Coca-Cola Corporation, and member of the Alpha Chi Rho Fraternity.

Anthony Gabriel, professional football player and member of The Fraternity of Phi Gamma Delta.

Ruth Stafford Peale, religious leader, public speaker, author and co-founder, publisher and chairman of the board of Guideposts, Inc. and member of the Alpha Phi Sorority,

Nancy Harvey Steorts, president of Nancy Harvey Steorts International consulting firm, former chairwoman of the U.S. Consumer Product Safety Commission under President Ronald Reagan, consultant to the director of the U.S. Office on Consumer Affairs at the White House, and special assistant for consumer affairs to the Secretary of Agriculture during the Nixon and Ford administrations, and member of the Alpha Phi Sorority.

Jackie Martin, first woman photo and art editor of the Washington Herald in 1931, and, later, war correspondent and director of photo operations for the Marshall Plan and member of the Delta Gamma Sorority;

Robin Burns, retired as Victoria's Secret Beauty Corporation’s CEO, former president and CEO of Estee Lauder Companies Inc.'s North American operations and it’s Donna Karan Cosmetics brand, and member of the Kappa Kappa Gamma Sorority.

In addition, 29 current members and 19 emeritus members of the Syracuse University Board of Trustees are fraternity and sorority members. These individuals are distinguished for their leadership is the worlds of finance, real estate, law, philanthropy, and public relations, to name a few.